Harp, Joel M. : rechercher sur Z-Library

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Articles (51)
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1

Why do obese patients not lose more weight when treated with low-calorie diets? A mechanistic perspective

Heymsfield, Steven B, Harp, Joyce B, Reitman, Marc L, Beetsch, Joel W, Schoeller, Dale A, Erondu, Ngozi, Pietrobelli, Angelo

Journal:

American Journal of Clinical Nutrition

Année:

2007

Langue:

english

Fichier:

PDF, 235 KB

english, 2007

2

Environmental fate and effects of nicotine released during cigarette production

Joel A. Seckar, Mari S. Stavanja, Paul R. Harp, Yongsheng Yi, Charles D. Garner, Jon Doi

Journal:

Environmental Toxicology and Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 211 KB

english, 2008

3

Discovery of VU6005649, a CNS Penetrant mGlu7/8 Receptor PAM Derived from a Series of Pyrazolo[1,5-a]pyrimidines

Abe, Masahito, Seto, Mabel, Gogliotti, Rocco G, Loch, Matthew T., Bollinger, Katrina A, Chang, Sichen, Engelberg, Eileen M, Luscombe, Vincent B, Harp, Joel, Bubser, Michael, Engers, Darren W., Jones,

Journal:

ACS Medicinal Chemistry Letters

Année:

2017

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2017

4

ChemInform Abstract: Semisynthesis of 6-Chloropurine-2′-deoxyriboside 5′-Dimethoxytrityl 3′-(2-Cyanoethyl-N,N-diisopropylamino)phosphoramidite and Its Use in the Synthesis of Fluorescently Labeled Oligonucleotides.

Md. Jashim Uddin, Michael I. Schulte, Leena Maddukuri, Joel Harp, Lawrence J. Marnett

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 30 KB

english, 2011

5

Preparative separation of nucleosome core particles containing defined-sequence DNA in multiple translational phases

Joel M. Harp, Elise L. Palmer, Melissa H. York, Andreas Gewiess, Matthew Davis, Dr. Gerard J. Bunick

Journal:

ELECTROPHORESIS

Année:

1995

Langue:

english

Fichier:

PDF, 492 KB

english, 1995

6

Mcg in 2030: new techniques for atomic position determination of immune complexes

B. Leif Hanson, Gerard J. Bunick, Joel M. Harp, Allen B. Edmundson

Journal:

Journal of Molecular Recognition

Année:

2002

Langue:

english

Fichier:

PDF, 451 KB

english, 2002

7

Macromolecular data collection with cryogenic helium

B Leif Hanson, Joel M Harp, Kristin Kirschbaum, Damon A Parrish, David E Timm, Andrew Howard, A Alan Pinkerton, Gerard J Bunick

Journal:

Journal of Crystal Growth

Année:

2001

Langue:

english

Fichier:

PDF, 216 KB

english, 2001

8

Expedient placement of two fluorescent dyes for investigating dynamic DNA protein interactions in real time

Sanford H. Leuba, Syam P. Anand, Joel M. Harp, Saleem A. Khan

Journal:

Chromosome Research

Année:

2008

Langue:

english

Fichier:

PDF, 751 KB

english, 2008

9

Worker Exposure Standard for Phosphine Gas

Bill Pepelko, Joel Seckar, Paul R. Harp, James H. Kim, David Gray, Elizabeth L. Anderson

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 136 KB

english, 2004

10

The active site of the SET domain is constructed on a knot

Jacobs, Steven A., Harp, Joel M., Devarakonda, Srikripa, Kim, Youngchang, Rastinejad, Fraydoon, Khorasanizadeh, Sepideh

Journal:

Natural Structural Biology

Année:

2002

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2002

11

[New Comprehensive Biochemistry] Chromatin Structure and Dynamics: State-of-the-Art Volume 39 || The core particle of the nucleosome

Année:

2004

Langue:

english

Fichier:

PDF, 44 KB

english, 2004

12

Crystal structure and mechanism of a carbon–carbon bond hydrolase

David E Timm, Heather A Mueller, P Bhanumoorthy, Joel M Harp, Gerard J Bunick

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 1.18 MB

english, 1999

13

Structural Basis for Bile Acid Binding and Activation of the Nuclear Receptor FXR

Li-Zhi Mi, Srikripa Devarakonda, Joel M. Harp, Qing Han, Roberto Pellicciari, Timothy M. Willson, Sepideh Khorasanizadeh, Fraydoon Rastinejad

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 809 KB

english, 2003

14

Synthesis and Structure–Activity Relationships of 5,6,7-Substituted Pyrazolopyrimidines: Discovery of a Novel TSPO PET Ligand for Cancer Imaging

Tang, Dewei, McKinley, Eliot T., Hight, Matthew R., Uddin, Md. Imam, Harp, Joel M., Fu, Allie, Nickels, Michael L., Buck, Jason R., Manning, H. Charles

Journal:

Journal of Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 892 KB

english, 2013

15

Total Synthesis of Stemaphylline N -Oxide and Related C9a-Epimeric Analogues

Schulte, Michael L., Turlington, Mark L., Phatak, Sharangdhar S., Harp, Joel M., Stauffer, Shaun R., Lindsley, Craig W.

Journal:

Chemistry - A European Journal

Année:

2013

Langue:

english

Fichier:

PDF, 794 KB

english, 2013

16

Structural and Chemical Aspects of Resistance to the Antibiotic Fosfomycin Conferred by FosB from Bacillus cereus

Thompson, Matthew K., Keithly, Mary E., Harp, Joel, Cook, Paul D., Jagessar, Kevin L., Sulikowski, Gary A., Armstrong, Richard N.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 1.51 MB

english, 2013

17

Discovery of the First M 5 -Selective and CNS Penetrant Negative Allosteric Modulator (NAM) of a Muscarinic Acetylcholine Receptor: ( S )-9b-(4-Chlorophenyl)-1-(3,4-difluorobenzoyl)-2,3-dihydro-1 H -imidazo[2,1- a ]isoindol-5(9b H )-one (ML375)

Gentry, Patrick R., Kokubo, Masaya, Bridges, Thomas M., Kett, Nathan R., Harp, Joel M., Cho, Hyekyung P., Smith, Emery, Chase, Peter, Hodder, Peter S., Niswender, Colleen M., Daniels, J. Scott, Conn,

Journal:

Journal of Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 716 KB

english, 2013

18

Microwave-assisted, one-pot reaction of 7-azaindoles and aldehydes: a facile route to novel di-7-azaindolylmethanes

Uddin, Md. Imam, Buck, Jason R., Schulte, Michael L., Tang, Dewei, Saleh, Samir A., Cheung, Yiu-Yin, Harp, Joel, Manning, H. Charles

Journal:

Tetrahedron Letters

Année:

2014

Langue:

english

Fichier:

PDF, 2.56 MB

english, 2014

19

Structure and Function of the Genomically-Encoded Fosfomycin Resistance Enzyme, FosB, from Staphylococcus Aureus

Thompson, Matthew K., Goodman, Michael, Keithly, Mary, Hammer, Neal, Cook, Paul, Jagessar, Kevin, Harp, Joel, Skaar, Eric, Armstrong, Richard N.

Journal:

Biophysical Journal

Année:

2014

Langue:

english

Fichier:

PDF, 44 KB

english, 2014

20

Crystal Structure of a Luteoviral RNA Pseudoknot and Model for a Minimal Ribosomal Frameshifting Motif †,‡

Pallan, Pradeep S., Marshall, William S., Harp, Joel, Jewett, Frederic C., Wawrzak, Zdzislaw, Brown, Bernard A., Rich, Alexander, Egli, Martin

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 921 KB

english, 2005

21

Methylation of Histone H3 by Coactivator-Associated Arginine Methyltransferase 1 †

Schurter, Brandon T., Koh, Stephen S., Chen, Dagang, Bunick, Gerard J., Harp, Joel M., Hanson, B. Leif, Henschen-Edman, Agnes, Mackay, Douglas R., Stallcup, Michael R., Aswad, Dana W.

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 148 KB

english, 2001

22

Analysis of the Structure and Function of YfcG from Escherichia coli Reveals an Efficient and Unique Disulfide Bond Reductase

Wadington, Megan C., Ladner, Jane E., Stourman, Nina V., Harp, Joel M., Armstrong, Richard N.

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 3.60 MB

english, 2009

23

Exploring Symmetry as an Avenue to the Computational Design of Large Protein Domains

Fortenberry, Carie, Bowman, Elizabeth Anne, Proffitt, Will, Dorr, Brent, Combs, Steven, Harp, Joel, Mizoue, Laura, Meiler, Jens

Journal:

Journal of the American Chemical Society

Année:

2011

Fichier:

PDF, 66 KB

2011

24

Correction to Analysis of the Structure and Function of YfcG from Escherichia coli Reveals an Efficient and Unique Disulfide Bond Reductase

Wadington, Megan C., Ladner, Jane E., Stourman, Nina V., Harp, Joel M., Armstrong, Richard N.

Journal:

Année:

2010

Fichier:

PDF, 565 KB

2010

25

Exploring Symmetry as an Avenue to the Computational Design of Large Protein Domains

Fortenberry, Carie, Bowman, Elizabeth Anne, Proffitt, Will, Dorr, Brent, Combs, Steven, Harp, Joel, Mizoue, Laura, Meiler, Jens

Journal:

Journal of the American Chemical Society

Année:

2011

Langue:

english

Fichier:

PDF, 2.09 MB

english, 2011

26

Structure and Function of YghU, a Nu-Class Glutathione Transferase Related to YfcG from Escherichia coli

Stourman, Nina V., Branch, Megan C., Schaab, Matthew R., Harp, Joel M., Ladner, Jane E., Armstrong, Richard N.

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 3.22 MB

english, 2011

27

2-Hydroxychromene-2-carboxylic Acid Isomerase: A Kappa Class Glutathione Transferase from Pseudomonas putida †,‡,§

Thompson, Lawrence C., Ladner, Jane E., Codreanu, Simona G., Harp, Joel, Gilliland, Gary L., Armstrong, Richard N.

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 3.64 MB

english, 2007

28

Structure and Function of the Genomically Encoded Fosfomycin Resistance Enzyme, FosB, from Staphylococcus aureus

Thompson, Matthew K., Keithly, Mary E., Goodman, Michael C., Hammer, Neal D., Cook, Paul D., Jagessar, Kevin L., Harp, Joel, Skaar, Eric P., Armstrong, Richard N.

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 3.26 MB

english, 2014

29

DNA Sequence Patterns in Precisely Positioned Nucleosomes

Uberbacher, Edward C., Harp, Joel M., Bunick, Gerard J.

Journal:

Journal of Biomolecular Structure and Dynamics

Année:

1988

Langue:

english

Fichier:

PDF, 997 KB

english, 1988

30

Semisynthesis of 6-Chloropurine-2′-deoxyriboside 5′-Dimethoxytrityl 3′-(2-Cyanoethyl- N,N -diisopropylamino)Phosphoramidite and its Use in the Synthesis of Fluorescently Labeled Oligonucleotides

Uddin, Md. Jashim, Schulte, Michael I., Maddukuri, Leena, Harp, Joel, Marnett, Lawrence J.

Journal:

Nucleosides Nucleotides & Nucleic Acids

Année:

2010

Langue:

english

Fichier:

PDF, 282 KB

english, 2010

31

Structural Basis of Duplex Thermodynamic Stability and Enhanced Nuclease Resistance of 5′- C -Methyl Pyrimidine-Modified Oligonucleotides

Kel′in, Alexander V., Zlatev, Ivan, Harp, Joel, Jayaraman, Muthusamy, Bisbe, Anna, O′Shea, Jonathan, Taneja, Nate, Manoharan, Rajar M., Khan, Saeed, Charisse, Klaus, Maier, Martin A., Egli, Martin, Ra

Journal:

Journal of Organic Chemistry

Année:

2016

Langue:

english

Fichier:

PDF, 3.57 MB

english, 2016

32

Total Synthesis of Actinophenanthroline A

Garcia-Barrantes, Pedro M., Harp, Joel R., Lindsley, Craig W.

Journal:

Tetrahedron Letters

Année:

2016

Langue:

english

Fichier:

PDF, 707 KB

english, 2016

33

ChemInform Abstract: Microwave-Assisted, One-Pot Reaction of 7-Azaindoles and Aldehydes: A Facile Route to Novel Di-7-azaindolylmethanes.

Uddin, Md. Imam, Buck, Jason R., Schulte, Michael L., Tang, Dewei, Saleh, Samir A., Cheung, Yiu-Yin, Harp, Joel, Manning, H. Charles

Journal:

Année:

2014

Fichier:

PDF, 21 KB

2014

34

ChemInform Abstract: Total Synthesis of Stemaphylline N-Oxide (II) and Related C9a-Epimeric Analogues (III) and (IV).

Schulte, Michael L., Turlington, Mark L., Phatak, Sharangdhar S., Harp, Joel M., Stauffer, Shaun R., Lindsley, Craig W.

Journal:

Année:

2014

Fichier:

PDF, 22 KB

2014

35

Effects of Sufentanil on Regional Cerebral Glucose Utilization in Rats

Young, Marie L., Smith, David S., Greenberg, Joel, Reivich, Martin, Harp, James R.

Journal:

Année:

1984

Fichier:

PDF, 480 KB

1984

36

Discovery, characterization and biological evaluation of a novel (R)-4,4-difluoropiperidine scaffold as dopamine receptor 4 (D4R) antagonists

Jeffries, Daniel E., Witt, Jonathan O., McCollum, Andrea L., Temple, Kayla J., Hurtado, Miguel A., Harp, Joel M., Blobaum, Anna L., Lindsley, Craig W., Hopkins, Corey R.

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2016

Langue:

english

Fichier:

PDF, 652 KB

english, 2016

37

Evaluation of TSPO PET Ligands [18F]VUIIS1009A and [18F]VUIIS1009B: Tracers for Cancer Imaging

Tang, Dewei, Li, Jun, Buck, Jason R., Tantawy, Mohamed Noor, Xia, Yan, Harp, Joel M., Nickels, Michael L., Meiler, Jens, Manning, H. Charles

Journal:

Molecular Imaging and Biology

Année:

2016

Langue:

english

Fichier:

PDF, 4.33 MB

english, 2016

38

Chirality Dependent Potency Enhancement and Structural Impact of Glycol Nucleic Acid Modification on siRNA

Schlegel, Mark K, Foster, Donald J., Kel'in, Alexander V, Zlatev, Ivan, Bisbe, Anna, Jayaraman, Muthusamy, Lackey, Jeremy G., Rajeev, Kallanthottathil G, Charisse, Klaus, Harp, Joel, Pallan, Pradeep S

Journal:

Journal of the American Chemical Society

Année:

2017

Langue:

english

Fichier:

PDF, 946 KB

english, 2017

39

Structure and evolution of ENTH and VHS/ENTH-like domains in tepsin

Archuleta, Tara L., Frazier, Meredith N., Monken, Anderson E., Kendall, Amy K., Harp, Joel, McCoy, Airlie J., Creanza, Nicole, Jackson, Lauren P.

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 1.41 MB

english, 2017

40

4′-C-Methoxy-2′-Deoxy-2′-Fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene Silencing

Malek-Adamian, Elise, Guenther, Dale, Matsuda, Shigeo, Martínez-Montero, Saúl, Zlatev, Ivan, Harp, Joel, Burai Patrascu, Mihai, Foster, Donald J., Fakhoury, Johans J., Perkins, Lydia, Moitessier, Nico

Journal:

Journal of the American Chemical Society

Année:

2017

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2017

41

A novel M1 PAM VU0486846 exerts efficacy in cognition models without displaying agonist activity or cholinergic toxicity

Rook, Jerri M., Bertron, Jeanette L, Cho, Hyekyung P., Garcia-Barrantes, Pedro M, Moran, Sean P, Maksymetz, James T, Nance, Kellie D, Dickerson, Jonathan W, Remke, Daniel H, Chang, Sichen, Harp, Joel,

Journal:

ACS Chemical Neuroscience

Année:

2018

Langue:

english

Fichier:

PDF, 962 KB

english, 2018

42

ChemInform Abstract: Total Synthesis of Actinophenanthroline A.

Garcia-Barrantes, Pedro M., Harp, Joel R., Lindsley, Craig W.

Journal:

Année:

2016

Fichier:

PDF, 14 KB

2016

43

Phosphorus SAD Phasing for Nucleic Acid Structures: Limitations and Potential

Harp, Joel, Pallan, Pradeep, Egli, Martin

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 3.57 MB

english, 2016

44

Structural basis for the synergy of 4′- and 2′-modifications on siRNA nuclease resistance, thermal stability and RNAi activity

Harp, Joel M, Guenther, Dale C, Bisbe, Anna, Perkins, Lydia, Matsuda, Shigeo, Bommineni, Gopal R, Zlatev, Ivan, Foster, Donald J, Taneja, Nate, Charisse, Klaus, Maier, Martin A, Rajeev, Kallanthottath

Journal:

Nucleic Acids Research

Année:

2018

Langue:

english

Fichier:

PDF, 2.77 MB

english, 2018

45

Cryo-neutron crystallographic data collection and preliminary refinement of left-handed Z-DNA d(CGCGCG)

Harp, Joel M., Coates, Leighton, Sullivan, Brendan, Egli, Martin

Journal:

Acta Crystallographica Section F Structural Biology Communications

Année:

2018

Langue:

english

Fichier:

PDF, 1.38 MB

english, 2018

46

Crystallization of a potassium ion channel and X-ray and neutron data collection

Langan, Patricia S., Vandavasi, Venu Gopal, Sullivan, Brendan, Harp, Joel, Weiss, Kevin, Coates, Leighton

Journal:

Acta Crystallographica Section F Structural Biology Communications

Année:

2019

Langue:

english

Fichier:

PDF, 431 KB

english, 2019

47

TCR- or Cytokine-Activated CD8+ Mucosal-Associated Invariant T Cells Are Rapid Polyfunctional Effectors That Can Coordinate Immune Responses

Lamichhane, Rajesh, Schneider, Marion, de la Harpe, Sara M., Harrop, Thomas W.R., Hannaway, Rachel F., Dearden, Peter K., Kirman, Joanna R., Tyndall, Joel D.A., Vernall, Andrea J., Ussher, James E.

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 4.85 MB

english, 2019

48

Type I interferons are important co‐stimulatory signals during T cell receptor mediated human MAIT cell activation

Lamichhane, Rajesh, Galvin, Henry, Hannaway, Rachel F, la Harpe, Sara M, Munro, Fran, Tyndall, Joel DA, Vernall, Andrea J, McCall, John L, Husain, Matloob, Ussher, James E

Journal:

European Journal of Immunology

Année:

2019

Langue:

english

Fichier:

PDF, 2.43 MB

english, 2019

49

Type I interferons are important co‐stimulatory signals during T cell receptor mediated human MAIT cell activation

Lamichhane, Rajesh, Galvin, Henry, Hannaway, Rachel F, la Harpe, Sara M, Munro, Fran, Tyndall, Joel DA, Vernall, Andrea J, McCall, John L, Husain, Matloob, Ussher, James E

Journal:

European Journal of Immunology

Année:

2019

Fichier:

PDF, 2.43 MB

2019

50

Neutrophils suppress mucosal‐associated invariant T cells in humans

Schneider, Marion, Hannaway, Rachel F., Lamichhane, Rajesh, la Harpe, Sara M., Tyndall, Joel DA, Vernall, Andrea J., Tony, A, Ussher, James Edgeworth

Journal:

European Journal of Immunology

Année:

2020

Langue:

english

Fichier:

PDF, 1.70 MB

english, 2020